Cytotoxic Activity Test Of Ethanolic Extract Of Berenuk Fruit (Crescentia Cujete L.) On Artemia Salina Leach Shrimp Larva Using Brine Shrimp Lethality Test (BSLT) Method

Abstract: Cancer is one of the leading causes human death in world. One therapies given to cancer patients chemotherapy which has cytotoxic effects. plants that have same effect berenuk or calabash (Crescentia cujete L.) plant, from family Bignoniaceae, grows wild and often referred as a poisonous plant. This plant contains napthoquinone chemical compounds other metabolite secondary such alkaloids, flavonoids, saponins, tannins, terpenoids, anthraquinones. The objective this study determine activity ethanolic extract fruit on Artemia salina Leach larva. BSLT (Brine Shrimp Lethality Test) method was used for study. powder flesh extracted using ethanol. obtained solvent evaporated rotary evaporator obtain thick extract. tested A. larva been prepared value mortality observed. result test had LC50 529.386 ppm categorized toxic.